Recent Publications

Updates

May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
July 2011
June 2011
April 2011

May 2012 Update

Marra, CA, Lynd LD, Grindrod KA, Joshi P, Isakovic A. Evaluating the Labour Costs Associated with Pharmacy Adaptation Services in British Columbia. CPJ/RPC March/April 2012, Vol 145, No. 2.

Marra CA, Lynd LD, Colley L, Harvard SS, Lacaille D, Schwenger E, Anis AH, Esdaile JM. Risk of Gastrointestinal Events in Patients with Rheumatoid Arthritis after Withdrawal of Rofecoxib. J Rheumatol. 2012 Mar 15. [Epub ahead of print].

Najafzadeh M, Lynd LD, Davis JC, Bryan S, Anis A, Marra M, Marra CA. Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment. Genet med 2012 Jan 19.doi: 10.1038/gim.2011.26 [Epub ahead of print].

Raymakers AJ, Sadatsafavi M, Marra F, Marra CA. Economic and humanistic burden of external genital warts. Pharmacoeconomics 2012 Jan 1;30(1):1-16. PMID: 22201520

Seto K, Marra F, Raymakers A, Marra CA. The Cost Effectiveness of Human Papillomavirus Vaccines: A Systematic Review. Drugs. 2012 Mar 13. Doi: 102165/11599470-000000000-00000. [Epub ahead of print]. PMID: 22413761

Slobogean GP, Marra CA, Sadatsafavi M, Sanders DW; on behalf of the Canadian Orthopedic Trauma Society. Is Surgical Fixation for Stress-Positive Unstable Ankle Fractures Cost Effective? Results of a Multicenter Randomized Control Trial. J Orthop Trauma. 2012 Apr 2. [Epub ahead of print]

Soon, J, Levine, M. The role of pharmacists in rural practice. The Translator, Winter 2012, Volume 6, Issue 1. Canadian Pharmacists Association.

April 2012 Update

Aikawa N, Okubo Y, Lynn M, Rossignol DP, Wong YN, Schuck E, Kitahara Y, Nakano T, Sivak O, Wasan KM, Nagy C, Yen M. Safety, pharmacokinetics and pharmacodynamics of four-hour intravenous infusions of eritoran in healthy Japanese and Caucasian men. Innate Immun. 2012 Mar 29.

Low A (Pro), McCormack J (Con). Point counterpoint - Should all elderly women receive bisphosphonates to prevent osteoporotic fractures? CJHP 2012; 65(1):45-48.

Wilby KJ, Lau TTY, Gilchrist SE, Ensom MHH. Mosquirix (RTS,S): A Novel Vaccine for the Prevention of Plasmodium falciparum Malaria. Ann Pharmacother. 2012 Mar;46:384-93.

March 2012 Update

Andolfatto G, Abu-Laban RB, Zed PJ, Staniforth SM, Stackhouse S, Moadebi S, Willman E. Ketamine-propofol combination (ketofol) versus propofol alone for emergencydepartment procedural sedation and analgesia: a randomized double-blind trial. Ann Emerg Med 2012; 59: doi:10.1016/j.annemergmed. 2012.01.017.

Fleischer JG, Rossignol D, Francis GA, Chan T, Lynn M, Wasan KM. Deactivation of the lipopolysaccharide antagonist eritoran (E5564) by high-density lipoprotein-associated apolipoproteins. Innate Immun. 2012 Feb;18(1):171-8. Epub 2011 Mar 7. PMID: 21382909

Ibrahim F, Gershkovich P, Sivak O, Wasan EK, Wasan KM. Assessment of novel oral lipid-based formulations of amphotericin B using an in vitro lipolysis model. Eur J Pharm Sci. 2012 Feb 18. PMID: 22369857

Kendrick J, Warkentin D, Ensom MHH. The Impact of Obesity on Pharmacokinetics and Dosing of Leukemia Chemotherapy. In: Cancer and Energy Balance, Hematological Malignancies. S Mittelman (ed); New York, NY: Springer. 2012.

Lau AJ, Yang G, Rajaraman G, Baucom CC, Chang TKH. Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor. Drug Metabolism and Disposition 40: 178-186, 2012.

Leung VWY, Soon JA, Levine M. Measuring and reporting of the treatment effect of hormonal emergency contraceptives. Pharmacotherapy 2012;32:210-21.

Wang, F., Wang, Y., Zhang, D., Puthanveetil, P., Johnson, J., Abrahani, A., and Rodrigues, B. Altered endothelial cell metabolism following high fatty acid is regulated by nuclear entry of heparanase. Arteriosclerosis Thrombosis and Vascular Biology 32: 406-414, 2012.

Zeng XL, Thumati, NR, Fleisig HB, Hukezalie KR, Savage SA, Giri N, Alter BP, Wong JMY. The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita. Human Molecular Genetics 21: 721-729, 2012.

February 2012 Update

Gershkovich P, Sivak O, Contreras-Whitney S, Darlington JW, Wasan KM. Assessment of cholesterol absorption inhibitors nanostructured aluminosilicate and cholestyramine using in vitro lipolysis model: J Pharm Sci. 2012 Jan;101(1):291-300.

Lau AJ, Yang G, Chang TKH. Isoform-selective activation of human constitutive androstane receptor by Ginkgo biloba extract: Functional analysis of the SV23, SV24, and SV25 splice variants. Journal of Pharmacology and Experimental Therapeutics 339: 704-715, 2011.

Lau AJ, Yang G, Rajaraman G, Baucom CC, Chang TKH. Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor. Journal of Pharmacology and Experimental Therapeutics 336: 816-826, 2011.

Mah G, Mabasa VH, Chow I, Ensom MHH. Evaluating Outcomes Associated with Alternative Dosing Strategies for Piperacillin/Tazobactam: A Qualitative Systematic Review. Ann Pharmacother. 2012;46:265-75. DOI 10.1345/aph.1Q378

Phillips JC, Oliffe JL, Ensom MHH, Bottorff JL, Bissell LJL, Boomer J, O'Brien KM, Howard T, Khara M, Bottorff JL. An Overlooked Majority: HIV-Positive Gay Men Who Smoke. Journal of Men's Health. 2012; online ahead of print; doi:10.1016/j.jomh.2011.11.003

Saatchi K, Gelder N, Gershkovich P, Sivak O, Wasan KM, Kainthan RK, Brooks DE, Häfeli UO. Long-circulating non-toxic blood pool imaging agent based on hyperbranched polyglycerols: Int J Pharm. 2012 Jan 17;422(1-2):418-27.

January 2012 Update

Edwards A, Ensom MHH. Pharmacokinetic Effects of Bariatric Surgery. Ann Pharmacother. Published Ahead of Print 20 Dec 2011, 10.1345/aph.1Q414.

Ensom MHH. Improving the Chances of Manuscript Acceptance: How to Address Peer Reviewers’ Comments. Can J Hosp Pharm. 2011;64:389-91.

Gilchrist SE, Letchford K, Burt HM. The solid-state characterization of fusidic acid. Int J Pharm. (2011). In press. doi:10.1016/j.ijpharm.2011.11.005.

Greanya E, Poulin E, Partovi N, Shapiro RJ, Al-Khatib M, Ensom MHH. Pharmacokinetics of Tacrolimus and Mycophenolate and its Glucuronidated Metabolites in Stable Renal Transplant Recipients on a Steroid-Free Regimen. Am J Health-Syst Pharm. 2012;68:134-42.

Jackson JK, Letchford K, Wasserman BZ, Ye L, Hamad WY, Burt HM. Int J Nanomedicine. The use of nanocrystalline cellulose for the binding and controlled release of drugs. 2011;6:321-30.

Jackson J, Leung F, Duncan C, Mugabe C, Burt H. The use of bone cement for the localized, controlled release of the antibiotics vancomycin, linezolid, or fusidic acid: effect of additives on drug release rates and mechanical strength. Drug Deliv. and Transl. Res. 2011. 1(2): 121-131.

Jackson JK, Pirmoradi FN, Wan CP, Siu T, Chiao M, Burt HM. Increased accumulation of paclitaxel and doxorubicin in proliferating capillary cells and prostate cancer cells following ultrasound exposure. Ultrasonics. 2011 Dec;51(8):932-9.

Marra F, Hajek J, Alasaly K, Coleman J, Van der Kopp M, Taylor D, and Lester, R. The use of mobile phones and text messaging to improve adherence to treatment of latent TB infection: a feasibility study. BC Centre for Disease Control Annual Research Symposium, Vancouver, British Columbia, November 7-8, 2011.

Mugabe C, Liggins RT, Guan D, Manisali I, Chafeeva I, Brooks DE, Heller M, Jackson JK, Burt HM. Development and in vitro characterization of paclitaxel and docetaxel loaded into hydrophobically derivatized hyperbranched polyglycerols. Int J Pharm. 2011 Feb 14;404(1-2):238-49.

Mugabe C, Matsui Y, So AI, Gleave ME, Baker JH, Minchinton AI, Manisali I, Liggins R, Brooks DE, Burt HM. In vivo evaluation of mucoadhesive nanoparticulate docetaxel for intravesical treatment of non-muscle-invasive bladder cancer. Clin Cancer Res. 2011 May 1;17(9):2788-98.

Mugabe C. Matsui Y, So AI, Gleave ME, Brooks DE, Burt HM. In vivo efficacy of intravesical paclitaxel and docetaxel loaded hydrophobically derivatized hyperbranched polyglycerols. Nanomedicine, (2011). In press DOI: 10.2217NNM.11.

Mugabe C, Matsui Y, So AI, Gleave ME, Heller M, Zeisser-Labouèbe M, Heller L, Chafeeva I, Brooks DE, Burt HM. In vitro and in vivo evaluation of intravesical docetaxel loaded hydrophobically derivatized hyperbranched polyglycerols in an orthotopic model of bladder cancer. Biomacromolecules. 2011 Apr 11;12(4):949-60.

Pirmoradi FN, Jackson JK, Burt HM, Chiao M. On-demand controlled release of docetaxel from a battery-less MEMS drug delivery device. Lab Chip. 2011 Aug 21;11(16):2744-52.

Saatchi K, Gelder N, Gershkovich P, Sivak O, Wasan KM, Kainthan RK, Brooks DE, Hafeli UO. Long-circulating non-toxic blood pool imaging agent based on hyperbranched polyglycerols: Int J Pharm. 2012 Jan 17;422(1-2):418-27.

Su VCH, Harrison J, Rogers C, Ensom MHH. Belatacept: A New Biologic and its Role in Kidney Transplantation. Ann Pharmacother. Published Online, 3 Jan 2012, DOI 10.1345/aph.1Q537.

Teng JFT, Mabasa VH, Ensom MHH. The Role of Therapeutic Drug Monitoring of Imatinib in Chronic Myeloid Leukemia (CML) and Metastatic or Unresectable Gastrointestinal Stromal Tumor (GIST) Patients. Ther Drug Monit. 2011; Dec 30 [Epub ahead of print] PMID: 22215488.

Tsallas A, Jackson J, Burt H. The uptake of paclitaxel and docetaxel into ex vivo porcine bladder tissue from polymeric micelle formulations. Cancer Chemother Pharmacol. 2011 Aug;68(2):431-44.

Wright A, Marra F, Chong M, Patrick DM. Moxifloxacin utilization in British Columbia after its unrestricted addition to the provincial formulary. 51st Interscience Conference Antimicrobial Agents Chemotherapy (ICAAC), Chicago, Illinois, September 17-20, 2011.

Ye L, Letchford K, Heller M, Liggins R, Guan D, Kizhakkedathu JN, Brooks DE, Jackson JK, Burt HM. Synthesis and characterization of carboxylic acid conjugated, hydrophobically derivatized, hyperbranched polyglycerols as nanoparticulate drug carriers for cisplatin. Biomacromolecules. 2011 Jan 10;12(1):145-55.

Young F, Marra F. A systematic review of intradermal vaccines. Vaccine 2011;29(48):8788-8801.

Zed PJ, Ensom MHH, Slavik RS, Brown G, Wilbur K, Kanji S, Koshman S, Irvine-Meek J, Perreault M, Zelenitsky S. Evaluation of the Research Grant Program of the Foundation of the Canadian Society of Hospital Pharmacists, 1995-2008. Can J Hosp Pharm. 2011;6:399-404.

December 2011 Update

Barry AR, Ensom MHH. A New Analogy for Teaching the Well-Stirred Model to Pharmacy Students. The International Journal of Pharmacy Education and Practice (IJPEP). 2011;7:1-7.

Chakraborti M, Jackson JK, Plackett D, Brunette DM, Burt HM. Drug
intercalation in layered double hydroxide clay: application in the
development of a nanocomposite film for guided tissue regeneration. Int J
Pharm. 2011 Sep 15;416(1):305-13.

Leung VWY, Levine M, Soon JA. Evaluating emergency contraceptives using
the preovulatory/postovulatory method. Pharmacotherapy
2011;31:496e-497e.

Mugabe C, Raven PA, Fazli L, Baker JH, Jackson JK, Liggins RT, So AI,
Gleave ME, Minchinton AI, Brooks DE, Burt HM. Tissue uptake of docetaxel
loaded hydrophobically derivatized hyperbranched polyglycerols and
their effects on the morphology of the bladder urothelium. Biomaterials.
2012 Jan;33(2):692-703.

Pirmoradi FN, Jackson JK, Burt HM, Chiao M. A magnetically controlled
MEMS device for drug delivery: design, fabrication, and testing. Lab
Chip. 2011 Sep 21;11(18):3072-80.

Sih K, Campbell SG, Tallon JM, Magee K, Zed PJ. Ketamine in adult
emergency medicine: controversies and recent advances. Ann Pharmacother
2011;45:1525-35.

Virani AS, Bezchlibnyk-Butler K, Jeffries JJ et al. Clinical handbook of psychotropic drugs, 19th Edn. Cambridge, MA: Hogrefe & Huber Publishers, 20011.

Wilby KJ, Ensom MHH. Pharmacokinetics of Antimalarials in Pregnancy: A Systematic Review. Clinical Pharmacokinetics. 2011;50:705-23.

Wang EHZ, Mabasa VH, Loh GW, Ensom MHH. A Review of Haloperidol Dosing Strategies in the Treatment of Delirium in the Critically-Ill. Neurocritical Care. 2011 (Online FirstTM) DOI: 10.1007/s12028-011-9643-3.

November 2011 Update

Anthony CJ, Karim S, Ackroyd-Stolarz S, Fry A, Murphy NG, Christie R, Zed PJ. Intensity of anticoagulation with warfarin and risk of adverse events in patients presenting to the emergency department. Ann Pharmacother 2011;45:881-7.

Guo N, Marra CA, Fitzgerald JM Elwood RK, Anis AH, Marra F. Patient preference for latent tuberculosis infection preventative treatment: a discrete choice experiment. Value in Health 2011;14(6):937-43.

Hohl CM, Nosyk B, Kuramoto L, Zed PJ, Brubacher JR, Abu-Laban RB, Sheps SB, Sobolev B. Outcomes of emergency department patients who present with adverse drug events. Ann Emerg Med 2011;58:270-9.

Marra F, Marra CA, Richardson K, Lynd L, Fitzgerald JM. Are we treating wheeze with bug killer? BMC Pulmonary Medicine 2011:11:32.

MacQuarrie K, Zed PJ. Airway Pharmacology In: Kovacs G, Law JA, editors. Airway Management in Emergencies, 2nd ed., Connecticut: People’s Medical Publishing House-USA; 2011. p. 267-98.

Mustafa S, Sharma V, McNeill JH. Insulin resistance and endothelial dysfunction: are epoxyeicosatrienoic acids the link? Exp Clin Cardiol 14 (2): e41–e50, 2009.

Nagareddy PR, Chow F, Hao L, Wang X, Nishimura T, MacLeod KM, McNeill JH, Fernandez-Patron C. Maintenance of adrenergic vascular tone by MMP-transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis. Cardiovascular Research 84:368-377, 2009.

Sharma V, Abraham T, So A, Allard MF, McNeill JH. Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria. Mol Cell Biochem 337:223-237 (doi:10.1007/s11010-009-0303-2), 2010.

Sharma V, Dhillon P, Parsons H, Allard MF, McNeill JH. Metoprolol represses PGC-1α-mediated carnitine palmitoyltransferase-1 ß expression in the diabetic heart. European Journal of Pharmacology 607:156-166, 2009.

Sharma V, McNeill JH. To scale or not to scale: The principles of dose extrapolation. Br J Pharmacol 157:907-921, 2009.

Sharma VJ, McNeill JH. Parallel effects of ß-adrenoceptor blockade on cardiac function and fatty acid oxidation in the diabetic heart: Confronting the maze. World J Cardiol 3(9):281-302, 2011.

Sharma V, Mustafa S, Patel N, Wambolt RF, Allard MF, McNeill JH. Stimulation of cardiac fatty acid oxidation by leptin is mediated by a nitric oxide/ p38 MAPK-dependent mechanism. Eur J Pharmacol 617:113-117, 2009.

Sharma V, Sharma A, Saran V, Bernatchez PN, Allard MF, McNeill JH. ß-receptor antagonist treatment prevents activation of cell death signaling in the diabetic heart independent of its metabolic actions. Eur J Pharmacol 657:117-125 (doi:10.1016/j.ejphar.2011.01.044), 2011.

Thompson KH, Lichter J, LeBel C, Scaife MC, McNeill JH, Orvig C. Vanadium treatment of type 2 diabetes: a view to the future. J Inorg Biochem 103(4):554-558, 2009.

Twiddy AL, Cox ME, Wasan KM. Knockdown of scavenger receptor class B Type I reduces prostate specific antigen secretion and viability of prostate cancer cells. Prostate. 2011 Oct 24. doi: 10.1002/pros.21499. [Epub ahead of print]

Vasudevan H, Lau S, Jiang J, McNeill JH. Effects of insulin resistance and testosterone on the participation of cyclooxygenase isoforms in vascular reactivity. J Exper Pharmacol 2:169-179, 2010.

Vasudevan H, Tran LT, McNeill JH. Insulin resistance, blood pressure and sex hormones. In: Insulin Resistance: Symptoms, Causes and Treatment, Chapter 3. Moliere J and Gauthier L (Eds.), Nova Science Publishers Inc., 2009.

Wang M, Fitzgerald JM, Richardson K, Marra CA, Cook VJ, Hajek J, Elwood RK, Bowie WR, Marra F. Use of Antibiotics Delays Diagnosis of Tuberculosis. International Journal of Tuberculosis and Lung Disease 2011; 15(8):1062-8.

Wilby K, Marra CA, da Silva J, Grubisic M, Harvard S, Lynd LD. Randomized Controlled Trial Evaluating Pictogram Augmentation of HIV Medication Information. Ann Pharmacother November 2011 vol. 45 no. 11 1378-1383.

Young F, Marra F. A systematic review of intradermal vaccines. Vaccine 2011 [epub].

Zed PJ. Adverse drug events and hospital pharmacy practice: thinking outside our box [Editorial]. Can J Hosp Pharm 2011;64:305-6.

October 2011 Update

Cleary JD and Wasan, KM. Amphotericin B: A new look at cell binding. The Open Antimicrobial Agents Journal , published on-line, October 2011.

Ensom MHH, Stephenson MD. A Two-Center Study on the Pharmacokinetics of Intravenous Immunoglobulin Before and During Pregnancy in Healthy Women with Poor Obstetrical Histories. Hum Reprod. 2011;26:2283-8.

Gershkovich P, Sivak O, Wasan EK, Lin M, Zhao J, Owen D, Clement JG, Wasan, KM. Tropically stable oral ormulation of amphotericin B (iCo-010): Biodistribution and toxicity, Lipids Health and Disease, Published on-line August 8, 2011.

Hafeli UO, Ensom MHH, Kiang TKL, Stoeber B, Chua B, Pudek M, Schmitt V. Comparison of Vancomycin Concentrations in Blood and Interstitial Fluid: a Possible Model for Less Invasive Therapeutic Drug Monitoring. Clin Chem Lab Med. 2011 Sep 26. [Epub ahead of print]

Harrison MJ, Bansback NJ, Marra CA, Drummond M, Tugwell PS, Boonen A. Valuing health for clinical and economic decisions: directions relevant for rheumatologists. J Rheumatol. 2011 Aug;38(8):1770-5.

Hubball, H., & Pearson, M. L. (2011). Scholarly approaches to curriculum evaluation: Critical contributions for undergraduate degree program reform in a Canadian context. In M. Saunders, P. Trowler, & V. Bamber (Eds.), Reconceptualising evaluative practices in higher education: The practice turn. Berkshire, UK: Open University Press Publishers/McGraw-Hill.

Johnson JA, Bowker SL, Richardson K, Marra CA. Time-varying incidence of cancer after the onset of type 2 diabetes: evidence of potential detection bias. Diabetologia 2011 Jul 12 [Epub ahead of print]

Kevin Letchford, Anders Sodergard, David Plackett, Samuel E. Gilchrist, Helen M. Burt. Chapter 9: Lactide and Glycolide Polymers. In Biodegradable Polymers in Clinical Use and Clinical Development. Abraham J. Domb, Neeraj Kumar and Aviva Ezra, (Ed). Hoboken, New Jersey: John Wiley & Sons Inc.; 2011. p. 319-366.

Leon CG, Lee J, Bartlett K, Gershkovich P, Wasan EK, Zhao J, Clement JG, Wasan KM. In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines:Lipids Health Dis. 2011 Aug 20;10(1):144. [Epub ahead of print]

Pak, M.L., Lakowski, T.M., Thomas, D., Vhuiyan, M.I., Hüsecken, K., Frankel, A. A Protein Arginine N-Methyltransferase 1 and 2 Heteromeric Interaction Increases PRMT1 Enzymatic Activity. Biochemistry DOI: 10.1021/bi200644c.

Soon JA, Levine M. Rural pharmacy in Canada: pharmacist training, workforce capacity and research partnerships. Int J Circumpolar Health 2011;70(4):407-418.

Woolcott JC, Khan KM, Mitrovic S, Anis AH, Marra CA. The cost of fall related presentations to the ED: A prospective, in-person, patient-tracking analysis of health resource utilization. Osteoporos Int. 2011 Sep 3 [Epub ahead of print]

Young F, Ensom MHH. Pharmacokinetics of Aminoglycosides in the Chronic Spinal Cord Injury Population. Am J Health-Syst Pharm. 2011:68:1607-14.

July 2011 Update

Black E, Lau TTY, Ensom MHH. Vancomycin-Induced Neutropenia: Is it Dose- or Duration- Related? Ann Pharmacother. 2011;45:629-38. DOI 10.1345/aph.1P583.

Davis JC, Marra CA, Robertson MC, Najafzadeh M, Liu-Ambrose T. Sustained Economic Benefits of Resistance Training in Community –Dwelling Senior Women. J Am Geriatr Soc 2011 Jun 30. doi: 10.1111/j1532-5415.2011.03473.x [Epub ahead of print]

Ellert G, Low A, and Wade JP. The Osteoporosis Book: Bone Health. 3rd ed. Vancouver, Canada: Trelle Enterprises; 2011.

Ensom MHH, Decarie D, Rudolph S. Stability of Levetiracetam in Extemporaneously Compounded Suspensions. Can J Hosp Pharm. 2011;64:207-11.

Kagan L, Gershkovich P, Wasan KM, Mager DE. Physiologically based pharmacokinetic model of amphotericin B disposition in rats following administration of deoxycholate formulation (fungizone®): pooled analysis of published data. AAPS J. 2011 Jun;13(2):255-64. Epub 2011 Mar 23. PMID: 21431453.

Loewen P, Dahri K. Risk of bleeding with oral anticoagulants: an updated systematic review and performance analysis of clinical prediction rules. Annals of Hematology. 2011:1-10-10.

Low, A. Shared decision-making: Helping your patients decide. Canadian Pharmacists Journal: May 2011, Vol. 144, No. sp1, pp. S23-S23.

Schwenger E, Dumontet J, Ensom MHH. Does Olanzapine Warrant Therapeutic Drug Monitoring in Schizophrenia? Clin Pharmacokinet. 2011;50:415-28.

Stabler SN and Ensom MHH. Extended-Interval Aminoglycoside Therapy for Adult Patients with Febrile Neutropenia: A Systematic Review. Can J Hosp Pharm. 2011;64:182-91.

't Hart P, Lakowski TM, Thomas D, Frankel A, Martin NI. (2011) Peptidic Partial-Bisubstrates as Inhibitors of the Protein Arginine N-Methyltransferases. ChemBioChem 12, 1427-1432.

Thornton SJ, Wong IT, Neumann R, Kozlowski P, Wasan KM. Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model. Lipids Health Dis. 2011 Jun 28;10(1):107. [Epub ahead of print] PMID: 21711516.

Pless SA, Galpin JG, Frankel A, Ahern CA. (2011) Molecular Basis for Class Ib Anti-Arrhythmic Inhibition of Cardiac Sodium Channels. Nature Communications 2, 351.

Woolcott J, Khan K, Mitrovic S, Anis A, Marra CA. The cost of fall related presentations to the ED: A prospective, in-person, patient-tracking analysis of health resource utilization. Osteoporosis International (accepted June 2011).

June 2011 Update

Ayas NT, Pack A, Marra CA. The Demise of Portable Monitoring to Diagnose OSA? Not So Fast! Sleep 2011, June 1;34(6):691-2.

Davis JC, Marra CA, Liu-Ambrose TY. Falls-related self-efficacy is independently associated with quality-adjusted life years in older women. Age Ageing. 2011 Mar 24. [Epub ahead of print]

Davis JC, Marra CA, Robertson MC, Najafzadeh M, Liu-Ambrose T. Sustained economic benefits of resitance training among community-dwelling senior women. Journal of the American Geriatrics Society (accepted December 2010).

Henrich N, Lynd LD, Joshi P, Grindrod K, Marra CA. Family physicians’ perceptions of pharmacy adaptation services in British Columbia. Can Pharm J 2011, In press.

Marra CA, Bansback, N, Anis AH, Shojania K. Introduction to economic modeling for clinical rheumatologists: application to biologic agents in rheumatoid arthritis. Clin Rheumatol. 2011 Feb 26 Epub ahead of print PMID: 21359506.

Marra CA, Lynd L, Harvard S., Grubisic M. Agreement between aggregate and individual-level measures of income and education: a comparison across three patient groups. BMC Health Services Research 2011, 11:69.

Marra F, Marra CA, Richardson KJ, Lynd LD, Fitzgerald JM. Antibiotic Consumption in Children Prior to Diagnosis of Asthma. BMC Pulmonary Medicine 2011, 11:32.

Ogrodniczuk JS, Lynd LD, Joyce AS, Grubisic M, Piper WE, Steinberg PI. Predicting response to day treatment for personality disorder. Can J Psychiatry. 2011 Feb;56(2):110-7.

April 2011 Update

Allan GM, Ivers N, McCormack J. Type 2 diabetes and ASA. Can Fam Physician. 2010; 56:664.

Babovic S, Wasan KM. Impact of the trade-related aspects of intellectual property rights (TRIPS) agreement on India as a supplier of generic antiretrovirals. J Pharm Sci. 2011 Mar;100(3):816-21. doi: 10.1002/jps.22326. Epub 2010 Aug 25. PMID: 20740678.

Brown S, Babovic S, Wasan KM. Increasing access to essential medicines: diversifying Canada's approach. J Pharm Sci. 2011 Feb;100(2):411-5. doi: 10.1002/jps.22300. No abstract available. PMID: 20653047.

Cantarovich M, Brown NW, Ensom MHH, Jain A, Kuypers DRJ, Van Gelder T, Tredger JM. Mycophenolate Monitoring in Liver, Thoracic, Pancreas and Small Bowel Transplantation: a Consensus Report. Transplantation Reviews. 2011: 25:65-77.

Ensom MHH, Decarie D, Lakhani A. Stability of Vancomycin 25 mg/mL in Ora-Sweet: Water (1:1) in Oral Cups and Plastic Bottles Under Refrigeration and at Room Temperature. Can J Hosp Pharm. 2010;63:366-72.

Gershkovich P, Wasan KM, Sivak O, Lysakowski S, Reid C, Premalatha K, Werbovetz KA. Simultaneous Determination of A Novel Antitrypanosomal Compound (OSU-36) and its Ester Derivative (OSU-40) in Plasma by HPLC: Application to First Pharmacokinetic Study in Rats. J Pharm Pharm Sci. 2011;14(1):36-45. PMID: 21501551

Kagan L, Gershkovich P, Wasan KM, Mager DE. Physiologically Based Pharmacokinetic Model of Amphotericin B Disposition in Rats Following Administration of Deoxycholate Formulation (Fungizone®): Pooled Analysis of Published Data. AAPS J. 2011 Mar 23. [Epub ahead of print] PMID: 21431453.

Man SSK, Carr RR, Ensom MHH. Comparison of Continuous versus Intermittent Intravenous Vancomycin Infusion: A Systematic Review. Can J Hosp Pharm. 2010;63:373-81.

McCormack JP. Should IV Antibiotics Be Administered by Prolonged Infusion? The Con Side. Can J Hosp Pharm 2010;63: 248-9.

McCormack JP. Allan GM. Measuring hsCRP - An important part of a Comprehensive Risk Profile or a Completely Redundant Practice? PLOS Medicine 2010,7: e1000196. doi:10.1371/journal.pmed.1000196.

McCormack JP, Allan GM, Virani AS. Is Bigger Better? An argument for “very” low initial doses. CMAJ 2011;183: 65-9.

Mustafa S, Vasudevan H, Yuen VG, McNeill JH. Renal expression of arachidonic acid metabolizing enzymes and RhoA/Rho kinases in fructose insulin resistant hypertensive rats. Mol Cell Biochem 333(1):203-209 (doi: 10.1007/s11010-009-0220-4), 2010.

Nagareddy PR, MacLeod KM, McNeill JH. GPCR agonist-inducd transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin resistant rats. Cardiovasc Res 87(1):177-186 (doi: 10.1093/cvr/cvq030), 2010.

Okoli CTC, Khara M, Torchalla I, Ensom MHH, Oliffe JL, Bottorff JL, Stanley PJ. Sex Differences in Smoking Cessation Outcomes of a Tailored Program for Individuals with Substance Use Disorders and Mental Illness. Addictive Behaviors. 2011;36:523-36. doi:10.1016/j.addbeh.2010.12.029.

Poulin E, Greanya E, Partovi N, Shapiro RJ, Al-Khatib M, Ensom MHH. Development and Validation of Limited Sampling Strategies for Tacrolimus and Mycophenolate in Steroid-Free Renal Transplant Regimens. Ther Drug Monit. 2011;33:50-5.

Reid CS, Patrick DA, He S, Fotie J, Premalatha K, Tidwell RR, Wang MZ, Liu Q, Gershkovich P, Wasan KM, Wenzler T, Brun R, Werbovetz KA. Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorg Med Chem. 2011 Jan 1;19(1):513-23. Epub 2010 Nov 5. PMID: 21112788.

Seto K, Dumontet J, Ensom MHH. Risperidone in Schizophrenia: Is there a Role for Therapeutic Drug Monitoring? Therapeutic Drug Monit. 2011 Mar 23. [Epub ahead of print] PMID: 21436762.

Strong DK, Decarie D, Ensom MHH. Stability of Levothyroxine in Sodium Chloride for Intravenous Administration. Can J Hosp Pharm. 2010; 63:437-43.

Su V, Greanya E, Ensom MHH. Impact of Mycophenolate Mofetil Dose Reduction on Allograft Outcomes in Kidney Transplant Recipients on Tacrolimus-Based Regimens: A Systematic Review. Ann Pharmacother. 2011;45:248-57. DOI 10.1345/aph.1P456.

Ting LSL, Benoit-Biancamano M, Bernard O, Riggs KW, Guillemette C, Ensom MHH. Pharmacogenetic Impact of UDP-Glucuronosyltransferase Metabolic and Multidrug Resistance-Associated Protein 2 Transport Pathway on Mycophenolic Acid in Thoracic Transplant Recipients: An Exploratory Study. Pharmacotherapy. 2010;30:1097-108.

Twiddy AL, Leon CG, Wasan KM. Cholesterol as a potential target for castration-resistant prostate cancer. Pharm Res. 2011 Mar; 28(3):423-37. Epub 2010 Aug 4. PMID: 20683646.

Vasudevan H, Lau S, Jiang J, McNeill JH. Effects of insulin resistance and testosterone on the participation of cyclooxygenase isoforms in vascular reactivity. J Exper Pharmacol 2:169-179, 2010.

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