Sajad War


About the Students

E-mail: sajad@interchange.ubc.ca

Training

Degree: M. Pharm.
Specialization: Pharmaceutical Sciences
Institution: Jamia Hamdard University
Year: 2002
Degree: B. Pharm.
Specialization: Pharmaceutical Sciences
Institution: Jamia Hamdard University
Year: 2000

Current Position

Position: Ph. D. Candidate
Supervisor: Dr. Ujendra Kumar

Scholarships + Awards

Name: Four Year Fellowship
Organization: University of British Columbia
Period: 2010–2013
Name: Graduate Student Travel Award
Organization: Faculty of Pharmaceutical Sciences
Period: 2010
Name: Graduate Award
Organization: Faculty of Pharmaceutical Sciences
Period: 2009, 2010
Name: Presidential Poster Award
Organization: The Endocrine Society
Period: 2009
Name: Teaching Assistant Appreciation Award
Organization: Faculty of Pharmaceutical Sciences
Period: 2009
Name: University Gold Medal for Best Academic Performance
Organization: Jamia Hamdard University
Period: 2002
Name: Junior Research Fellowship
Organization: University Grants Commission, Government of India
Period: 2000–2002

 

About The Research

Somatostatin via somatostatin receptor subtypes (SSTR1-5) is known to mediate antiproliferative effects, and in particular SSTR3 is distinctly associated with apoptosis. However, the molecular mechanisms responsible for the pro-apoptotic role of SSTR3 are still elusive and it is not known which segment of the receptor participates in apoptosis. My research project will focus on understanding the molecular signals in SSTR3 that contribute to apoptosis.

Publications + Presentations

Publications
  • Somvanshi R.K., War S.A., Chaudhari N., Qiu X., Kumar U. Receptor specific crosstalk and modulation of signaling upon heterodimerization between β1-adrenergic receptor and somatostatin receptor-5. Cell. Signal. 2011 May; 23(5):794-811.
  • War S.A., Somvanshi R. K., Kumar U. Somatostatin receptor-3 mediated intracellular signaling and apoptosis is regulated by its cytoplasmic terminal. Biochim. Biophys. Acta. 2011 Mar; 1813(3):390-402.
Conference Abstracts and Poster Presentations
  • Somvanshi R.K., War S.A., Chaudhari N., Kharmate G., Rajput P.S., Bakshi D., Qiu X. and Kumar U. (2010) The Presence of Somatostatin Receptor 5 Modulates β1-Adrenergic Receptor Mediated Signaling Pathways. Endocrine Reviews, S1, 31(3): S179.
  • Somvanshi R.K., War S.A., Chaudhari N., Kharmate G., Rajput P.S., Bakshi D., Qiu X. and Kumar U. (2010) Somatostatin Receptor 5 and β2-Adrenergic Receptor Crosstalk Modulates Intracellular Signaling. Endocrine Reviews, S1, 31(3): S180.
  • War S.A., Foot E.A. Somvanshi R.K., Chaudhari N., Kharmate G., Rajput P.S., Bakshi D., Qiu X., Laher I. and Kumar U. (2010) Expression of somatostatin receptors in the diabetic brain of db/db mouse model. Endocrine Reviews, S1, 31(3): S182.
  • Somvanshi R.K., War S.A., Chaudhari N., Kharmate G., Rajput P.S., Bakshi D., Qiu. X. and Kumar U. (2010) SSTR5 and β1AR blocks SST mediated inhibition of cAMP and signaling in receptor specific manner. The Journal of Heart Disease, Vol 7(1), 115.
  • Somvanshi R.K., War S.A., Chaudhari N., Kharmate G., Rajput P.S., Bakshi D., Qiu X. and Kumar U. (2010) Modulation of apoptotic and calcineurin-mediated NFAT dephosphorylation in cells coexpressing SSTR5 and β2AR. The Journal of Heart Disease, Vol 7(1), 116.
  • Rajput P.S., Kharmate G., Somvanshi R.K., Qiu X., War S.A., Bakshi D. and Kumar U. Somatostatin Receptors 1-5 Colocalization with DARPP-32 in Rat Brain in Region and Receptor Specific Manner. Canadian Association for Neuroscience (CAN) and the Canadian College of Neuropsychopharmacology (CCNP), May 15-18, 2010 Ottawa, Canada.
  • War S.A., Somvanshi R.K. and Kumar U. Somatostatin receptor-3 mediated regulation of cell signaling and apoptosis. ENDO 09: Washington, DC, June 10-13, 2009.
  • Somvanshi R.K., Kharmate, G., Rajput, P.S., War S.A. and Kumar U. Role of C-tail in homo-and heterodimerization of human somatostatin receptor type-4 (hSSTR4): implication in receptor internalization and cell signaling. ENDO 09: Washington, DC, June 10-13, 2009.

 

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